Contamination free cryo-EM sample preparation

Obtain high-quality cryo-EM samples by minimizing ice contamination during sample preparation.

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Protect your sample against ice contamination

Our research indicates that nearly 40% of cryo samples become contaminated with ice. The crystalline ice formed on or within the sample can obscure the region of interest and significantly lower the cryo-EM data quality. The CERES Clean Station and Vitri-Lock protect your precious sample against ice formation, enabling you to capture high-resolution structures.

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Advantages of CERES sample preparation

Moisture-free cryo-EM sample preparation

Ice-contamination-free cryo-ET sample transfer

Better sample preservation

Clean and moisture-free cryo-EM sample preparation

Prepare your cryo-EM samples in the highly effective CERES Clean Station, which provides a clean and moisture-free (< 0.01% water) environment, facilitating the preparation of grids for single particle analysis (SPA) or cryo-electron tomography (cryo-ET). The station consists of three modules specifically designed for cryo AutoGrid assembly, shuttle loading, and cassette loading.

Safe cryo-ET lamellae transfer

Ensure safe and ice contamination-free transfer of your cryo-ET samples between the Clean Station and the cryo-FIB/SEM with the CERES Vitri-Lock. This unique high-vacuum cryo-sample transfer system allows for a safe transfer time of up to 30 minutes, ensuring your samples remain vitrified without the need to rush between stations.

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Explore your options

Reach out to our team of specialists to find out how CERES can make your sample preparation process more comfortable and more effective.

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Partners

Innovating with experts in the field

“With these powerful tools, we were able to streamline the cryo-FIB/SEM automation process. Since there is no contamination visible, we were able to polish our lamellae automatically to a thickness of less than 150 nm.”

Dr. Sebastian Tacke Max Planck Institute of Molecular Physiology