A common challenge in the cryo-EM workflows is to keep samples vitrified and ice contamination free. Ice contamination can happen in various steps of the cryo-EM workflow whenever moisture in the sample environment condenses onto the cryo-sample. The effects of ice contamination on the cryo-samples can be devastating in some cases – obscuring rare events, wasting cell samples that took weeks to prepare, or even precious human patient samples.
In order to tackle this issue, CERES Ice Defence System is tailored to minimize ice contamination at the different steps of your cryo electron microscopy (cryo-EM) workflow – preparation, transfer and lamella generation, with corresponding tools – CERES Clean Station, CERES Vitri-Lock and CERES Ice Shield. Together, these tools aim to help you obtain the highest quality cryo-EM samples, with higher throughput and world-class results. No more wasted time on complex sample preparation which results in unusable lamellae. Instead, spend more time focusing on what really matters: understanding the building blocks of life with cryo-EM and getting closer to the next breakthrough.
This work is supported by the European SME2 grant № 879673.