The SECOM SR is an integrated platform for correlative light and electron microscopy which uses super-resolution (SR) optical microscopy in combination with an electron microscope. This system possesses all the features of the SECOM system, but is equipped with an extremely powerful optical microscope for yet more detail down to the nanoscale to study the complex relation between form and function in biology.
In recent years, super-resolution microscopy has proven itself to be an extremely powerful technique in biological research. With the invention of SR microscopy, it is now possible to precisely localize biomolecules at length scales that were previously only accessible using electron microscopy. Especially at this length scale, it is important to visualize and understand the micro-environment of these biomolecules; resolution only becomes truly valuable with contextual information.
With the automated overlay procedure of the SECOM SR platform, EM and FM images are always aligned perfectly. Using the automated overlay, time can be spent acquiring rather than aligning data and since the overlay procedure is unbiased it truly strengthens your scientific discoveries.
Because only the highest quality optical components are used, the SECOM SR ensures the best optical performance of any integrated system. One of the unique features is the possibility to use vacuum compatible immersion oil.